21th September 2018 - The Nisin Market is expected to grow at a considerable CAGR, on a world scale, over the forecast period. It is a vertical market with downstream end user applications like beverages, dairy products, meat, canned vegetables, and bakery products et all. The market ecosystem is comprised of raw material suppliers, natural preservatives and natural food ingredient manufacturers, regulatory bodies, and the end user industries. Rising disposable income and growing population in emerging markets, busy lifestyle, lack of a potential alternative, and increase in demand for convenience food that is safe are the key market drivers.
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Complementary health benefits of Nisin like termination of Tumor cells and prevention of tooth decay, FDA/WHO approvals for using it as a preservative and in active packaging, and its use in thermal as well as non-thermal treatment (in combination with high pressure and high intensity pulsed electric fields) are driving the Nisin market exponentially. Other applications like an agent in veterinary, healthcare, and pharmaceutical products, and as an agent for isolation of yeast, gram-negative bacteria, and moulds will open new avenues for the Nisin market on the forecast horizon. However, disadvantages of Nisin like less effectiveness in high fat foods and adsorption to the surface of protein globules, flavor alteration in dairy products, resistance development by microbes, inhibition of beneficial microflora, and proteolytic enzymes in raw roods that may inactivate nisin are restraining market growth.

Nisin is a bactericidal polypeptide that inhibits closely related species that are spoilage bacteria, thus acts as a preservative without hampering taste and color. It is a byproduct of lactic acid fermentation with working mechanisms like cell death, leakage of molecules, bind to receptor, and pore formation. It is commonly known as Nisin Bacteriocin. It works best in combination with other antimicrobial (Monolaurin, LPS, or other bacteriocins) and in low fat having pH value less than 6. Nisin is usually produced by a fermentation process using Lactococus bacteria. To overcome the disadvantages of nisin, it was microencapsulated in phospholipid vescicles and tested on Cheddar cheese. This improved its stability, distribution, and efficacy; as cited in International Dairy Journal in 2003. Nisin is the only natural preservative approved by FDA as well as WHO.
Nisin market is segmented on the basis of geographical region. The geographical regions for this market are Asia Pacific, Europe, North America, and Rest of the World (RoW). Meat segment currently holds the largest market share, particularly in US & Europe, due to high consumption of meat and seafoods in these regions. On the other hand, canned vegetables segment is expected to reach the high water mark in terms of CAGR in the forecast period due to various applications of nisin for preserving as well as active packaging of canned vegetables. North America leads the current Nisin market, with US on the forefront. This is due to the high demand for convenience foods which are minimally processed and have longer shelf-life. Asia Pacific region is expected to grow at the highest CAGR in the forecast period.
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Key players in the Nisin Market are Royal Dsm, Danisco, Galactic, Zhejiang Silver-Elephant Bioengineering, Shandong Freda Biotechnology, Handary, Chihon Biotechnology, and Siveele. Amongst the M&A activity in the Nisin market, Cayman Chemical acquired Biomol GmBH in January 2016. DuPont acquired Danisco AS in May 2011, and is now operated as a subsidiary of DuPont Denmark Holding APS. Meanwhile, Royal DSM NV leads the preservatives market in Europe.
Market segment by Type, the product can be split into
- Nisin A
- Nisin Z
Market segment by Application, Nisin can be split into
- Meat
- Dairy Products
- Beverages
- Bakery Products
- Canned Vegetables
- Others
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